Metabolic shift in density-dependent stem cell differentiation
نویسندگان
چکیده
منابع مشابه
Metabolic oxidation regulates embryonic stem cell differentiation
Metabolites offer an important unexplored complementary approach to understanding the pluripotency of stem cells. Using MS-based metabolomics, we show that embryonic stem cells are characterized by abundant metabolites with highly unsaturated structures whose levels decrease upon differentiation. By monitoring the reduced and oxidized glutathione ratio as well as ascorbic acid levels, we demons...
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ژورنال
عنوان ژورنال: Cell Communication and Signaling
سال: 2017
ISSN: 1478-811X
DOI: 10.1186/s12964-017-0173-2